![]() ![]() ![]() ![]() At birth the SDN contains only some 20% of the cells found at 2 to 4 years of age. Sexual differentiation to the human brain takes place much later than originally claimed. In other human research, two other hypothalamic nuclei (interstitial nuclei of the anterior hypothalamus 2 and 3) and part of the bed nucleus of the stria terminalis (BST) have been reported to be sexually dimorphic in the human. The magnitude of the difference is the SDN depends on age. We have called this cluster the sexually dimorphic nucleus (SDN). We have found that a cluster of cells in the preoptic area of the human hypothalamus contains about twice as many cells in young adult men as in women. Differences in size and cell number of various nuclei in the hypothalamus for homosexual versus heterosexual men have recently been reported in two studies. Recent brain research has revealed structural differences in the hypothalamus in relation to biological sex and sexual orientation. ![]()
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May 2023
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